این دو تا تفاوتی از لحاظ پیاده سازی با همدیگه ندارن ولی ویکیپدیا یه تفاوتش رو اینطوری گفته بود:
I²C is the basis for the
[Dear Guest/Member you can't see link before replyclick here to register], the
[Dear Guest/Member you can't see link before replyclick here to register] [Dear Guest/Member you can't see link before replyclick here to register] (DDC) interface, the
[Dear Guest/Member you can't see link before replyclick here to register] (SMBus),
[Dear Guest/Member you can't see link before replyclick here to register] (PMBus)and the Intelligent Platform Management Bus (IPMB, one of the protocols of
[Dear Guest/Member you can't see link before replyclick here to register]). These implementations have differences in voltage and clock frequency ranges, and may have
[Dear Guest/Member you can't see link before replyclick here to register].
TWI (Two Wire Interface) or TWSI (Two-Wire Serial Interface)
is essentially the same bus implemented on various system-on-chip processors from [Dear Guest/Member you can't see link before replyclick here to register] and other vendors.
[Dear Guest/Member you can't see link before replyclick here to register] Vendors use the name TWI, even though I²C is not a registered trademark. Trademark protection only exists for the respective logo (See upper right corner) and patents on I²C have now lapsed
این طور که من برداشت کردم احتمالا فقط محصولات اتمل از I2C به این اسم استفاده می کنن.